Menstrual cycles – basic information

Меոѕtruаtion means having your periods. During your periods, you will be bleeding from your uterus (womb) and the blood flows out from the vagina.
A woman will start getting their periods when they enter through puberty. They will continue to get their periods until they reach “menopause.” This is the time when periods naturally stop at average of 50 to 52 years old.

Basics

Periods occur due to certain hormonal effects on the inner lining of the uterus (womb). These elevated hormones are produced by the ovaries in a cyclical manner and occurs at the start of puberty. This is also the time when it is physically possible to get pregnant. During each cycle:
• The inner lining of the uterus starts to thicken due to the effects of oestrogen. This thickened lining is intended to support a pregnancy.
• One of the ovaries will start to produce an egg and will be release once it matured. This is termed as ovulation.
• Pregnancy occurs when the release egg is fertilized by the sperm. If no pregnancy occurs, then the thickened lining will be shed as bleeding and termed as a period (menstruation).
In many women, this cycle repeats itself about once a month. Some women may get an irregular menstrual cycle.

What is abnormal menstruation?
• You have heavy menses when you:
 Soak through a pad or tampon every 1 or 2 hours
 Need to change your pad or tampon several times during the night
 Pass clots or stains your clothes, undergarments or pajamas (term as flooding)
 Excessive flow will lead to anaemia – anaemia is a condition when your body doesn’t have enough red blood cells to carry oxygen to your tissues, making you feel weak, tired, headaches, having trouble breathing when you exercise or doing routine work, palpitation (feeling your heartbeat too fast) when you exercise.
• Have periods that last for more than 8 days
• Bleed in between periods
• Get your period more often such as 2 to 3 episodes in a month.
• Have moderate to severe pain and cramps in your lower belly before or while you are bleeding
• Suddenly bleeding again after you have not had periods for at least a year, and when you think that you are already menopausal.
There are many causes of abnormal menstrual bleeding. For more details, click HERE and HERE to read more.

Frequency of a period
At the beginning of puberty when a person first starts getting their period, the cycle may not be every month. Sometimes, it may even skip a month or two. This is still normal or may come more frequently. Fortunately, over time, most menstrual cycles tend to be more regular. Most women get a period about once a month. A normal cycle can range from 24 days to 38 days. The cycle length is counted from the first day of your last period to the first day of your next period. During each period, the flow usually lasts from a few days to about a week.
It is a good practise to keep track of your menstrual cycles and monitor the duration and amount of flow. You should then consult your doctor when there is a drastic change

Associated symptoms with menstruation
During menstruation, some women may have other symptoms, and this can occur either before or during the bleeding days. These symptoms are related to hormonal changes. If this happens before the start of menstruation, it is term as premenstrual syndrome (PMS). You can click on the link to read more.

What can affect my period?
It’s normal for your usual cycle to come a few days earlier or a few days late. Several factors may affect your menstrual cycles – either making it less often or not at all. These include:
• pregnancy
• breastfeeding
• heavy exercise especially the extreme form, feeling very stressed, or big changes in body weight
• certain health or endocrine problems, such “polycystic ovary syndrome (PCOS)” or thyroid disorders.
• certain medicines, including certain birth control pills
• peri-menopause (some women may enter menopause at a much earlier age)
If you do not have periods for extended period or the cycles are very irregular, your doctor may order some blood tests to find the cause for it.

What are the different types of menstrual products?
There are many different products you can use during your period. They include:
• Pads – this is the most popular and the pad is placed on the inner lining of the underwear to absorb the blood. Different sizes and thickness are available. Most pads sold are the disposable type.
• Tampons – this type is to be inserted into vaginal and are made of super absorbent material. During period, the tampon will expand slightly as it absorbs the menstrual blood. Some tampon comes with disposable applicators to help easy insertion into vagina. The tampons have a string that hangs outside of the vagina to make it easy to remove. It should be changed at least every 4 to 8 hours. Leaving a tampon in for too long is not advisable due to risk of infection.
• Menstrual cups – These are small, soft and flexible cups that is inserted into the vagina to collect the menstrual blood and prevent it from falling out. It comes indifferent brands and sizes. They can be worn for up to 12 hours. It can be washed and reused.
• Period underwear and swimwear – These are specially made underwear and swimwear that can be worn during menstruation. It can absorb blood. It can be washed and reused.
The choices depend on your own preference, your lifestyle and the type of activities that you may want to do during the menstruation. Some women may prefer to use tampons or menstrual cups during hiking or swimming instead of pads. Cost is also an issue for considerations. In the long term, reusable may be cheaper and more eco-friendly

Restriction during period
There is usually no restriction and most of the time a woman can do all her normal activities unless it is too heavy or associated with severe pain. In such instances, she should consult her doctor to find out why and get treated. There are no dietary restriction as well.

Steps to relieve period related discomfort
• Take pain relief medications such as ibuprofen, mefenamic acid, or naproxen. These are called Nonsteroidal anti-inflammatory drugs (NSAIDs), unless you have known allergies.
• Apply heat pad or hot water bottle on your lower belly – This can help relieve ϲrаmрѕ. Please be careful to avoid causing burn to your skin.
• For some women, regular exercise can help reduce menstrual cramps and pain. Therefore, it may be worthwhile to try and see if this helps you.

You should consult your doctor if you have the following:
• you still have not had your period by 15 years of age.
• your menstrual cycles are only 3 cycles or less in a year.
• the menstrual flow is progressively heavier with passage of large clots and flooding.
• the period pain is getting more severe.
• Heavy bleeding lasting more than a week.

Disclaimer

This is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. It is important for readers to seek proper medical advice when necessary.

Adenomyosis – an update

Adenomyosis is a benign uterine disease in which endometrial tissues (glands and stroma) are found within the myometrium (wall of the uterus). It has been described as endometriosis internal.

In a normal menstrual cycle, the endometrial tissue will grow, becomes thickened and then shed, resulting in the expected cyclical or monthly menstrual bleeding. If this happens in the uterine wall (myometrium), the resulting bleeding in the wall will cause pain. In the long term, the uterine wall will progressively thicken, thus producing a diffusely enlarged uterus. It often occurs along with other conditions that affect the pelvic organs, especially еոԁοmеtriosis. Αԁеոοmуoѕiѕ can also co-exist in people with fibroids, which are abnormal growths that form in the muscle of the uterus.

Causes

The cause of such growth in the uterine wall is not known. It may be related to repeated childbirths, pelvic endometriosis, increasing age and late childbirth. There is an increased association of pelvic endometriosis and adenomyosis in about 30% of cases. Other diagnosis commonly found in women with adenomyosis include fibroids and endometrial polyps.

Incidence

The exact incidence of the disease is unknown. It is generally estimated that 20% of women have adenomyosis. It is likely to be higher, due to the fact that many women are now delaying childbirth till a much later age.

This is a picture showing the uterine enlargement due to adenomyosis. The red patches represent the endometrial tissue, which bleeds during every menstrual cycle.

Clinical symptoms and signs

Some women with adenomyosis are asymptomatic and diagnosis is only made on histological examination of the uterus. Typical symptoms of adenomyosis are:

Heavy menstrual bleeding – this is due to increased uterine cavity bleeding surface area as a result of enlargement and inadequate uterine contraction.
Dysmenorrhea (menstrual or period pain) – the pain is usually severe and can be prolonged. The pain usually coincides with the timing of excessive menstrual flow. In some women, the pain may persist even after cessation of menses and present as chronic pelvic pain.
• Dyspareunia (painful sex) or frequency of urination—is due to the enlarged and tender uterus.
• Infertility: Women with adenomyosis have a higher incidence of infertility and miscarriage.
The examination may reveal:
• Tenderness in the lower abdomen during menses
• Enlarged uterus which is palpable per abdomen
• Anaemia due to excessive menstrual bleeding
• A uterus that is larger than normal (see diagram).

Diagnosis

The diagnosis of adenomyosis can only be confirmed via microscopic examination of the uterine specimen taken from the hysterectomy (after removal of the uterus). The diagnosis is often suspected from clinical history, examination, and imaging scans. An ultrasound scan of the pelvis will show mixed echogenicity in the uterine wall. The uterine wall is typically thickened and more commonly in the posterior wall. These findings may be confused with fibroids, and they may also co-exist. The more accurate imaging modality is Magnetic Resonance Imaging (MRI). It is more specific to the diagnosis and can differentiate adenomyosis from fibroids.

TREATMENT

The only definitive treatment for adenomyosis is total hysterectomy (removal of the uterus), with or without ovarian conservation. Some women may respond to medical therapy but eventually majority will need hysterectomy for cure. Therefore, early diagnosis is important because women with early adenomyosis respond better to medical therapies.

1. Medical therapies
• Tranexamic acids – this is given for reduction of heavy menstrual flow and to be taken at the start of menstrual bleeding for 2 to 4 days. It may help to relieve period pain as well if there is a reduction of menstrual flow.
• Painkillers – usually the non-steroidal anti-inflammatory drugs (NSAIDs) is the first choice such as mefenamic acid, diclofenac, ibuprofen and naproxen. For those who cannot tolerate it due to gastric side effects, COX-2 inhibitors such as celecoxib or etoricoxib tablets can be taken.

    Birth control pills – combined oral birth control pills can be use if there is additional need for contraception. This can help in reduction of menstrual flow and period pain. It is best if taken continuously for several packs before a break (pill free interval). This extended regime will reduce the number of menstrual bleeds in a year.
    • Progestogens – this is a synthetic hormone that induces thinning and atrophy of the endometrial tissue and reduces menstrual flow. It can be given orally or as an injection every 3 months (marketed as Depo-Provera). The oral progestogen is to be taken daily and the available formulations are: norethisterone, dienogest (Visanne), medroxyprogesterone acetate, dydrogesterone. The side-effects most commonly seen with progestogen usage include troublesome breakthrough uterine bleeding, weight gain, abdominal bloating, oedema, acne and mood changes. Progestogens are commonly used for endometriosis but can be prescribed as empirical therapy to reduce or even stop menstrual flow in adenomyosis.
    Intrauterine system (MIRENA) – Mirena is a hormonal intrauterine device (IUD) that releases a progestogen and can be used for contraception. The device is a T-shaped plastic frame that is inserted into the uterus and lasts for 5 years. The daily progestogen release will suppress or reduce menstrual bleeding and will help in improving pain and anaemia. However, Mirena will not be suitable for those who presented late with an enlarged uterus. The Mirena will not fit well in an enlarged uterine cavity and the response will be poor. Expulsion rate is also higher.
    Regular follow-up is required to assess response to therapy and to monitor the uterus size via clinical examination and ultrasound scan of the pelvis. Increasing pain and heavier menstrual flow with worsening anaemia suggest failure of medical therapies and is an indication for surgery.

    2. Uterine artery embolization (UAE) – has been offered in some centers for the treatment of symptomatic adenomyosis. It is a minimally invasive option to stop the main blood supply to the uterus. However, it is usually not done for women who might want to get pregnant. It is effective for those nearing perimenopausal age. For younger patients, there is a higher rate of symptom recurrence.

      3. Surgery – if the adenomyosis lesion is focal or localized, removal or burning of this abnormal area may be offered if keen for fertility or for uterus preservation. Ultimately, hysterectomy (removing the uterus) is often the best option for a cure. Oophorectomy (removal of the ovaries) at the same time is not required unless otherwise indicated.

      Disclaimer

      This is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. It is important for readers to seek proper medical advice when necessary.

      To print a pdf copy, click HERE

      Labour and delivery – When to go to the hospital?


      Most women (especially in their first pregnancy) are often unsure when to go to the hospital to give birth. Below is a list of symptoms and signs you should be aware of that will require you to go to the hospital for further evaluation.

      Symptoms and signs of Labour

      1. When your waters break, you will notice a clear or urine–like fluid coming out; the amount may vary from a gradual trickle to a sudden gush. If you notice a green or dark stain fluid; this may be meconium (the baby’s first poo) and can be a sign of foetal distress. There is a risk of infection if your waters break too soon before labour and the waters could bring the cord down as well, compressing your baby’s oxygen supply (however, this is very rare).
      2. You have some slight bleeding and often mixed with mucus. This is called “show” and arises from the plug that keeps the cervix closed. Labour can start any time after this, although it could be as long as a few days. This does not occur in every woman, so just because you have not seen yours it doesn’t mean you aren’t in labour.
      3. Having contractions – when contraction starts, it is usually irregular and mild. It will slowly progress to a more regular contractions, becoming stronger, last longer and come closer together. If this happens, then it is almost certainly labour.

      Foetal movement

      Fetal movement is an indicator of well-being. It is still normal for movement to slow down during the last few weeks as the head descends into the pelvis, and there will be less space for the foetus. However, if your baby is not moving at all for the whole day, or not moving as much as normal, you need to be seen as soon as possible. If you are unsure, please seek advice as soon as possible or go straight to labour room especially when you are already in the third trimester of pregnancy.

      Sometimes the pain or the contraction you felt may be classified as false labour. This occurs if:

      • it is irregular and infrequent.
      • slowly disappear and you feel the decreasing intensity or frequency when you change position, walk, or rest.
      • are not particularly uncomfortable and limited to your lower abdomen.
      • no progressive increase in discomfort and frequency of pain.
      • there are no cervical findings to suggest labour (this entails a vaginal examination by either the midwife or doctor to assess the opening of the uterus).

      However, you are likely to be in labour if:

      • there is progressive increase in frequency and intensity of the contraction, duration lasting usually 40 to 60 seconds.
      • persistent despite changing in position, walk, or rest.
      • associated with leakage of fluid (due to rupture of the membranes).
      • associated with changes in the cervix (progressive thinning and dilatation)

      Sometimes the only way you can know for sure whether you’re in labour is by seeing your health care provider as soon as possible. When you arrive at the hospital, your doctor, a nurse, a midwife, or a resident physician will perform an abdominal palpation to feel for contraction and also do a pelvic examination to determine whether you’re in labour. The practitioner also may hook you up to a monitor to see how often you’re contracting and to see how the foetal heart responds. In certain situation, your health care provider may advise you to stay under observation for several hours to see whether the situation is changing.

      To print a pdf file, please click HERE

      Labour and delivery – What to bring to the Hospital.

      This article will help you to prepare the essential items that you need to bring to the hospital for your labour and delivery. The preparation should be done when you are about eight months pregnant. Pack the items listed in the list below in a bag and place the bag in a convenient place that is easy for you or your spouse to retrieve it when needed.

      The list here is just a suggestion or a guide only, and you may make your own adjustments based on your preference. Decide which items you will need for your labour and birth, the hospital stay, and for the trip home for you and your baby.

      Read more

      Nausea & vomiting during pregnancy (NVP) (Morning Sickness in Pregnancy)

      This is common in the first three months of pregnancy and occurs in 50% to 80% of pregnant women. The symptoms often occur in the morning (from 6-9 am) but may occur at any time during the day. The impact and severity of the nausea and vomiting is different for each woman.

      SIGNS AND SYMPTOMS

      It ranges from mild to severe nausea with or without vomiting. This is usually during the first 12 to 14 weeks of pregnancy. It may continue longer, and for a few women, may last throughout pregnancy. By the end of the third month, most symptoms will resolve in the majority of women. The symptoms are more severe in those with multiple pregnancy or molar pregnancy.

      CAUSES

      The exact causes of nausea and vomiting during pregnancy are unknown. Nausea may result from rising levels of human chorionic gonadotrophin (pregnancy hormone) in the blood or other hormonal changes that take place to permit normal growth of the fetus.

      Read more

      Progestogen-only Injectable (POI) Contraception

      Progestogen-only injectable contraception is a hormonal type of contraception that is given through an injection. It contains a synthetic form of the hormone progesterone, known as progestin or progestogen. They provide protection against pregnancy for up to 8 to 14 weeks.

      Types

      • Medroxyprogesterone acetate (DMPA)
      • Norethisterone enanthate (NET-EN)

      Mechanism of action

      • This hormone works primarily by suppressing ovulation (preventing the release of an egg from the ovaries).
      • It also thickens cervical mucus, making it more difficult for sperm to reach and fertilize an egg.
      • It can thin out the uterine lining, making it less suitable for the development of the fertilized egg.

      Read more

      Progestogen only pill (POPs)

      This type of pill does not contain oestrogen and the dose of progestogen is significantly lower than in those used in combined oral contraceptive pills (COC). It is also called the “mini-pill” and is useful for women who do not want pills that contain oestrogen or in situations where the oestrogen is not suitable for medical reasons. They are a highly effective method of birth control when taken correctly.

      Formulation – Available formulations are:

      • Norethisterone 350 ug (NET) – (Noriday)
      • Levonorgestrel (LNG) 30 μg
      • Desogestrel (DSG) 75 μg – (Cerazette)

      Levonorgestrel (LNG) and norethisterone (NET) are grouped as “traditional’ POPs”

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      Wisdom versus Intelligence

      Article contributed by Dr Ong Tien Kwan (Klinik Ong)

      A wise action – whether through bodily action, verbal action or mental action – is an act that is beneficial to the doer, the recipient and the community. For example, an act of generosity is a wise action because it brings benefits to the doer, the recipient and the community. A wise person is one who acts wisely.

      In contrast, a foolish action is one that is harmful to oneself, to others and to the community. For example, a raging (angry) action brings harm to oneself, to others and to the community. A fool is one who thinks that his or her foolish action is beneficial to himself or herself, when in fact, it is not. Often, this is because he or she is only able to see the short-term gain but unable to see the long-term loss.

      Read more