Emergency Contraception (EC)

The main purpose of contraception (or birth control) is to prevent an unplanned pregnancy. Most methods of contraception enable sexually active couples to temporarily avoid pregnancy. Emergency contraception (or post-coital contraception) is used in preventing pregnancy after intercourse when standard contraceptives have failed, when no contraceptives were used at all or in cases of sexual assault. Emergency contraception is not considered an abortion. However, it is not recommended to be used as regular contraception. Emergency contraception is generally effective for birth control (75-90%), but effectiveness varies depending on the time of the woman’s menstrual cycle and the timing of the prior sexual activity.

Mechanism of actions – a single mechanism has not been established. EC methods are not abortifacient. Possible mechanisms are:
– Prevent or postpone ovulation.
– Causing genital tract to be hostile to sperm or blastocyst.
– Interferes with tubal transport.
– Preventing fertilisation (with IUD use).
– Blocking implantation (with IUD use).

Type of emergency contraception

1. Intrauterine Contraceptive Device (IUD or IUCD) – An IUD is a birth control device that is inserted into a woman’s uterus by a doctor

Insertion of copper IUD should not be more than five days after unprotected intercourse. This is suitable for those who desire long-term contraception. The placement has risks of pelvic infection and uterine injury, although these are quite rare. In a small group of women, long-term use of an IUD for birth control may cause certain side effects, such as heavy menstrual bleeding and painful menstrual cramps. It can be removed easily in the clinic if unsuitable.

This is the only method of EC that is effective after ovulation has taken place, therefore, making it the most effective method among all the emergency contraceptive choices and ideal for those who want long-term contraception.

2. Hormones pills:

A. Progesterone receptor modulator – the drug is ulipristal acetate, marketed as ella®.

It is given as 30 mg single oral dose, within 5 days (120 hours) after unprotected intercourse or contraceptive failure. This should be the hormonal emergency contraception of choice in view of the higher effectiveness and fewer side effects when compared to the levonorgestrel or combined hormonal contraception.

B. Progestogen-only emergency contraception – the hormone used is levonorgestrel. The dosage is 1.5 gm as a single dose. This is better than the divided dose of 0.75mg given 12 hours apart. Ideally, it should be taken within 72 hours of unprotected intercourse. Commercial brand available are Madonna, Postinor-2, Escapelle.

C. Combined hormonal contraception (Yuzpe regime) – each dose should consist of ethinyl oestradiol (EE) 100 mcg and levonorgestrel (LNG) 500 mcg. Two doses are required. There are no commercial brands available for this regimen. However, this can be made from a variety of available combined oral contraceptives pills in the market. The dosage sgould be taken within 72 hours of unprotected intercourse and repeat another dose in 12 hours.  This is the least effective among the oral pills.

The most effective EC method is the intrauterine device (IUD). The risk of pregnancy following placement of a copper IUD is 0.1%. For oral types, the most effective is ulipristal acetate, followed by the levonorgestrel. Data from trials comparing ulipristal acetate and levonorgestrel report respective pregnancy rates of 1.8% for ulipristal acetate versus 2.6% for levonorgestrel. However, it is important to take note that these are ideal situations and the failure rate is higher if oral EC is taken after ovulation or the  longer the interval between having unprotected intercourse and taking the EC. Higher body weight or BMI could also reduce the effectiveness of oral EC, particularly the levonorgestrel and Yutze regime.

Oral EC pills can be used more than once in a cycle. Repeated doses may result in more irregular bleeding and side effects. You should discuss this with your healthcare provider if you are planning to use this more than once in one cycle. In terms of contraindication, ulipristal should be avoided in women with severe asthma on oral steroids. Other than this, it is generally safe to use ulipristal and levonorgestrel in the majority of healthy women.

Disadvantages of Emergency Contraception

  • Not as effective as other forms of regular birth controls. 
  • Side effects include nausea, vomiting, headache, breast tenderness, bloated feeling and swelling of hands and feet. The side effects may be less with the ulipristal or levonorgestrel and more severe with the use of the combined oestrogen and progestogen formulation (Yutzpe regime).
  • Further contraception is required
  • Certain medications taken before or after the use of oral emergency contraception may reduce the efficacy – please discuss with your doctor regarding these drug interactions.

Following the use of EC, you should:

  • Use a barrier method until the next period.
  • If vomiting occurs within 3 hours of taking oral EC, a repeat dose should be given.
  • Talk to your health care provider regarding long-term contraception choices.
  • Seek medical advice if you experience unexpected side effects. Or if menses is delayed by more than seven days, or has abnormal flow, and you suspect that you may be pregnant.

Menses following administration of EC pills:

  • 75 to 90% menstruate within seven days (before or after) of their expected date of the next menses.
  • Menstrual bleeding will be late in the remaining 10 to 20%.

Disclaimer

This is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. It is important for readers to seek proper medical advice when necessary. 

Progestogen-only Injectable (POI) Contraception

Progestogen-only injectable contraception is a hormonal type of contraception that is given through an injection. It contains a synthetic form of the hormone progesterone, known as progestin or progestogen. They provide protection against pregnancy for up to 8 to 14 weeks.

Types

  • Medroxyprogesterone acetate (DMPA)
  • Norethisterone enanthate (NET-EN)

Mechanism of action

  • This hormone works primarily by suppressing ovulation (preventing the release of an egg from the ovaries).
  • It also thickens cervical mucus, making it more difficult for sperm to reach and fertilize an egg.
  • It can thin out the uterine lining, making it less suitable for the development of the fertilized egg.

Read more

Progestogen only pill (POPs)

This type of pill does not contain oestrogen and the dose of progestogen is significantly lower than in those used in combined oral contraceptive pills (COC). It is also called the “mini-pill” and is useful for women who do not want pills that contain oestrogen or in situations where the oestrogen is not suitable for medical reasons. They are a highly effective method of birth control when taken correctly.

Formulation – Available formulations are:

  • Norethisterone 350 ug (NET) – (Noriday)
  • Levonorgestrel (LNG) 30 μg
  • Desogestrel (DSG) 75 μg – (Cerazette)

Levonorgestrel (LNG) and norethisterone (NET) are grouped as “traditional’ POPs”

Read more

Vasectomy – Male contraception

Article contributed by Dr Peter Ng and Dr Beatrice Chua Yoong Ni

The aim of a vasectomy is to prevent sperm from reaching the semen by disconnecting the sperm duct. The resulting ejaculate is therefore sperm-free, eliminating the risk of pregnancy. Sort of like a cheap shark fin soup without the shark fins (sperms).

Vasectomy is the contraception of choice for 6%–8% of married couples worldwide. Vasectomy is a minor procedure that provides effective and permanent contraception. In fact, it is far more effective than many other methods of contraception, including female sterilization.

Prior to a vasectomy, it is important and both husband and wife be present together to be counseled by a specialist on the implications of the procedure. It is important that the completeness of family is ascertained and that both husband and wife had discussed beforehand and agreed that it is the husband who should undergo a vasectomy to attain permanent contraception.

Read more

Contraception – Hormonal implant (Implanon)

The main purpose of contraception (or birth control) is to prevent an unplanned pregnancy. You should know and understand the different types of methods available to you, the risks and benefits of each, and any possible side effects so that both you and your partner can able to make an informed choice. Contraception can be broadly divided into:

  1. Temporary or permanent methods – permanent birth control is accomplished through sterilization (tying or removal of the fallopian tubes) or hysterectomy (removal of womb/uterus). The rest of the methods are classified as temporary or reversible.
  2. Short term or long-term methods – short term methods are condoms and oral pills. Long term methods are injectables, intrauterine device and hormonal implants.

Hormone implant currently available is Implanon NXT®. It consists of a single plastic rod measuring 4 cm and contain a progestogen hormone called etonogestrel. Implanon is inserted surgically, just under the skin of the upper arm. The implant will release a minute amount of this hormone every day for 3 years. It works by preventing the monthly ovulation (the release of an egg from the ovary) during your menstrual cycle. It also thickens the vaginal mucus to prevent sperm from reaching the egg (fertilization). Continuous effect of the hormone will thin out the lining of the uterus (womb) to prevent attachment of a fertilized egg. Implanon does not contain any oestrogen.

Read more